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Research
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PubMed COVID-19 Clinical Care

5651 - 5660 of 44979 results found

On the origins of SARS-CoV-2 main protease inhibitors

Date
Monday, January 29, 2024 - 4:00 AM
Description
In order to address the world-wide health challenge caused by the COVID-19 pandemic, the 3CL protease/SARS-CoV-2 main protease (SARS-CoV-2-M^(pro)) coded by its nsp5 gene became one of the biochemical targets for the design of antiviral drugs. In

The impact of trained immunity in respiratory viral infections

Date
Monday, January 29, 2024 - 4:00 AM
Description
Epidemic peaks of respiratory viruses that co-circulate during the winter-spring seasons can be synchronous or asynchronous. The occurrence of temporal patterns in epidemics caused by some respiratory viruses suggests that they could negatively